MS Biomedical Sciences


Curriculum

FALL SEMESTER   SPRING SEMESTER
Code Course Name Credits   Code Course Name Credits
BIO 625 Advanced Molecular Biology 3   BIO 620 Advanced Cell Biology 3
MAT 610  Statistical Inference and Modeling 3   BIO 680 Bacterial Pathogenesis 3
BIO 6XX Immunology# 3   PAD 693  Epidemiology 3
BIO 660 Journal Club 1   BIO 660 Journal Club 1
COM 630  Intercultural Communication in Healthcare 3   PSC 625 Applied and Clinical Biochemistry 3
  Bioselective* 3   ETH 510 Healthcare and Human Values 3
Total Credits 16   Total Credits 16
SUMMER SEMESTER    
Code Course Name Credits        
BIO 6XX Capstone Thesis 3        
Total Credits 3      
                                     TOTAL CREDITS:    36        

*Bioselective Course- Students must select one course from the following courses:

  • Genetics & Molecular Basis of Disease
  • Infectious Disease Pharmacology
  • Public Health Microbiology
  • Clinical Microbiology I
  • Clinical Microbiology II
  • Hematology and Hemostasis

# Program Students who have completed UG Immunology coursework may choose to take BIO 627 Innate Immunology in place of BIO 6XX Immunology.

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COURSE DESCRIPTIONS

FALL SEMESTER

BIO 625 G 
Advanced Molecular Biology. This lecture-based course provides an in-depth analysis of the general concepts of molecular biology in prokaryotic and eukaryotic cells that occur in nature as well as those applied to the laboratory. The course consists of 3 parts. The first part of the course will focus on aspects of molecular biology that occur in nature. Topics presented will include detailed mechanisms of DNA organization, DNA replication, transcription, gene regulation, genetic recombination, translation, protein folding and degradation,and biochemistry of lipids and membrane formation. The second part of the course will focus on concepts of molecular biology that have been exploited for use in laboratory research. Topics will include cell growth and tissue culture, analysis and manipulation of DNA (DNA isolation, hybridization, PCR, sequencing, creation of knockouts/mutants, RNAi, qPCR, & RNA seq), the functions and importance of antibodies in research, recombinant protein expression and purification, and protein analysis/detection methods. The third part of the course will focus on scientific communication. In this part of the course students will give a journal-club style oral presentation on a topic in molecular biology. (3); Prerequisite: PSC 311/312 or CHE 312/313 or equivalent.

MAT 610 G 
Statistical Inference and Modeling. This course provides students with a basic knowledge of biostatistics. It includes methods of experimental design and data analysis used to make inference. Topics covered include confidence intervals,hypothesis testing, multivariable regression, generalized linear models, survival models and analysis of variance. The course will also include a component which introduces the students to statistical programming. (3)

BIO 660 G 
Journal Club. This course is designed to enhance the ability of graduate students to critically evaluate scientific articles published in juried scientific journals. Articles will be selected from current scientific literature in a variety of disciplines in the molecular biosciences, including cell biology, molecular biology, medicinal chemistry biochemistry, microbiology, immunology and infectious diseases. All participants will read and critique the articles. Each student will present at least two articles per semester. (1)

COM 630 G 

Health systems require practitioners to provide care to patients with diverse values, beliefs, experiences, and behaviors. This course exposes students to the communication challenges that patients and professionals navigate as part of an intercultural therapeutic partnership, with special emphasis on the ways in which health care and health promotion can be tailored to patients’ unique social, cultural, and linguistic needs. The course uses the term “culture” broadly and inclusively, highlighting traditional racial/ethnic notions of culture (Asian), national cultures (American), and co-cultures (African-American), while also including contemporary notions of cultural membership (cultures of medicine, cultures of disability, LGBTQ). Key topics include: minority health disparities, health literacy, barriers to health care access, cultural variations in communication style, the use of medical interpreters, traditional and complementary medicine, cultural notions of public and private, and culturally-specific media environments that influence health beliefs and behaviors.

 

SPRING SEMESTER

BIO 620 G 
Advanced Topics in Microbiology. This course will explore various cutting-edge topics in Microbiology through Journal club style presentations of primary literature from high impact peer reviewed journals. Each session will begin with a brief overview of the background information by the instructor followed by critical evaluation of the paper through student presentations and group discussions. The course will be divided in four broad themes. The first theme covers general microbial concepts including bacterial physiology and structure, metabolism and genetics. The second theme will explore the microbial virulence mechanisms, anti-microbials, and antibiotic resistance mechanisms, along with discussing novel prophylactic and therapeutic strategies for important bacterial infectious diseases. The third theme of the course will include the nature and biological activities of viruses, virus-host interactions and some important viral diseases. The last theme will focus on the important advances made in the field of host-pathogen interactions including innate and adaptive immune responses against selected pathogens. (1-3); Prerequisite: permission of the instructor

BIO 680 G 
Bacterial Pathogenesis. This course is designed to provide students with fundamental and cutting edge information on the molecular mechanisms of bacterial pathogenesis. Topics presented will include virulence factors, virulence regulation and evasion strategies utilized by bacteria to survive host defense mechanisms. Special emphasis will be placed on understanding the genetic, molecular, and biochemical approaches that can be used to study these host-pathogen interactions. Intervention strategies, including vaccination and anti-microbial therapy along with bacterial resistance mechanisms will also be discussed. Data analysis from primary literature will form a major component of the course. (3); Prerequisite: BIO 210, BIO 236, PSC 315, PSC 311 or CHE 311, PSC 312 or equivalent courses

PSC 500 G  

Applied and Clinical Biochemistry is foundational to medical science and will help students develop an understanding of biological molecules and their relationship to common disorders. Using applications and clinical correlations, the course will reinforce the role of enzymes as building blocks of life and in catalyzing and regulating biochemical reactions within the body.  The integration of various metabolic pathways, cellular metabolism, and biosynthesis with emphasis on the key concepts of structure and function of macromolecules involved in physiological processes will serve as the basis for an understanding of drug action and drug development. Biomolecular techniques related to clinical analysis will also be explored. This course will combine lecture discussion and assignments designed to enhance student learning. Upon the completion of this course, students will learn the applications and clinical implications of human biochemistry, the cellular basis for several common genetic diseases and metabolic disorders, and essential techniques related to clinical biochemistry.

HOI 645 G 
Epidemiology I (formerly PAD 693 G). This course covers the principles and methods of epidemiologic investigation including describing the patterns of illness in populations and research designs for investigating the etiology of disease. The course
introduces quantitative measures to determine risk, association and procedures for standardization of rates. It also reviews application of basic principles and methods in the design and conduct of epidemiologic studies. Topics include the development of research questions; overview of epidemiologic study designs; sampling, sample size, and selection bias; techniques for data collection, sources of secondary data, and the evaluation of measurement and information bias;confounding and effect modification; techniques for simple and stratified analyses; and an introduction to mathematical modeling in epidemiology. (3)