Stefan Balaz

Education

  • PhD and DSc, Comenius University, Bratislava, Slovakia
  • MS, Slovak University of Technology, Bratislava, Slovakia

Research Interests

The overall, long-term goal is to contribute to the understanding of processes affecting the fates and effects of drugs in the body, in terms of structures and properties of drugs and body components, by a concerted deployment of bench-top and computational techniques. The approaches can be divided into two main streams: Subcellular Pharmacokinetics and Drug-Receptor Interactions, which are integrated into Quantitative Structure-Time-Activity Relationships.

Learn More About Dr. Balaz

Subramaniam R, Lynch S, Cen Y, Balaz S. Polarity of Hydrated Phosphatidylcholine Headgroups. Langmuir (under review).

Natesan S, Lukacova V, Peng M, Subramaniam R, Lynch S, Wang Z, Tandlich R, Balaz S: Structure-based prediction of drug distribution across the headgroup and core strata of a phospholipid bilayer using surrogate phases. Mol Pharmaceutics 2014; 11: 5020-5048.

Lukacova V, Natesan S, Wang Z, Peng M, Subramaniam R, Lynch S, Tandlich R, and Balaz S: Structural determinants of drug partitioning in surrogates of phosphatidylcholine headgroup region, Mol Pharmaceutics 2013; 10: 3684-3696.

Natesan S, Balaz S: Rigorous incorporation of tautomers, ionization species, and different binding modes into ligand-based and receptor-based 3D-QSAR methods. Curr Pharm Des2013; 19: 4316-4322.

Balaz S: Does trans-bilayer diffusion play a role in membrane transport of drugs? Drug Discov Today 2012; 17: 1079-1087.

To learn more about Dr. Balaz’s research, visit NCBI MyBibliography .

Total: 136 papers, 19 chapters, 1 book

Krapah O,* Balaz S. Interaction of Amino Side Chains with the Surrogates of the Phospholipid Bilayer. ACPHS Student Summer Research Award Presentation, Albany NY, October 27, 2018 (Poster presenter: Opoku Krapah) *Recipient of an ACPHS Summer Student Research Award.

Member of the Editorial Boards of Current Computer-Aided Drug Design (Bentham) and Chemical Papers (Springer).

Peer reviewer of manuscripts for the Journal of Medicinal Chemistry, Journal of Chemical Information and Modeling, and Environmental Science and Technology.