Senthil Natesan, Ph.D.

Bio: 

Education

Ph.D., Pharmaceutical Sciences, North Dakota State University, Fargo, ND  
M. Tech., Bioinformatics, Indian Institute of Information Technology, Allahabad, India
Bachelor of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, India 

Courses Taught at ACPHS

Molecular Modeling 
Drug Properties Prediction

Selected Publications

Lukacova, Viera; Natesan, Senthil; Peng, Ming; Tandlich, Roman; Wang, Zhanbin; Lynch, Sandra; Subramaniam, Rajesh; Balaz, Stefan. Structural determinants of drug partitioning in surrogates of phosphatidylcholine bilayer strata. Mol. Pharmaceut. 2013 (DOI: 10.1021/mp400204y)

Natesan, Senthil; Wang, Zhanbin; Lukacova, Viera; Peng, Ming: Subramaniam, Rajesh; Lynch, Sandra; Tandlich, Roman; Balaz, Stefan. Structural determinants of drug partitioning in n-hexadecane/water system. J. Chem. Inf. Model. 2013, 53(6), 1424-1435.

Natesan, Senthil and Balaz, Stefan, Rigorous incorporation of tautomers, ionization species, and different binding modes into ligand-based and receptor-based 3D-QSAR methods, Curr. Pharm. Des. 2013, 19(23), 4316-4322. 

Natesan, Senthil; Subramaniam, Rajesh; Bergeron, Charles; and Balaz, Stefan: Binding affinity prediction for ligands and receptors forming tautomers and ionization species: Inhibition of mitogen-activated protein kinase-activated protein kinase 2 (MK2) inhibitors, J. Med. Chem. 2012, 55 (5), 2035–2047.

Natesan, Senthil; Wang, Tiansheng; Khandelwal, Akash; Lukacova, Viera; Bartus, Vladimir; Subramaniam, Rajesh; and Balaz, Stefan: cell-QSAR: Conceptual dissection of receptor binding and intracellular disposition in antifilarial activities of Selwood antimycins. J. Med. Chem. 2012, 55(8), 3699-3712.

Natesan, Senthil; Wang, Tiansheng; Khandelwal, Akash; Lukacova, Viera; Bartus, Vladimir; and Balaz, Stefan: Rigorous treatment of multi-species multi-mode ligand-receptor interactions in 3D-QSAR: CoMFA analysis of thyroxine analogs binding to transthyretin, J. Chem. Inf. Model. 2011, 51 (5), 1132-1150.

Assistant Professor
Department of Pharmaceutical Sciences - Vermont Campus