Mathangi Srinivasan, Ph.D.

Education

  • Professional development certificates - Project Management, Center for Continuing Education, University of Minnesota, Twin Cities
  • Ph.D., Molecular and Cell Biology, University of Maryland, College Park
  • M.S., Biological Sciences, Birla Institute of Technology and Science, Pilani, India

Research Interests

Developing new strategies to target cancer stem cells to arrest tumor growth and promote chemo sensitivity; understanding tumor-immune cell interactions to combat tumor immune suppression.

AWARDS

  • Travel Award, College of Life Sciences, UMD College Park
  • Award of Excellence, UMD College Park
  • Office of Research, grand prize winner, GRID 2007, UMD College Park
  • Zain-Ul-Abedin Annual Scholarship, Molecular and Cell Biology

Selected Publications

Srinivasan M, Panoskaltsis-Mortari A, Blazar B, et al. (2011) Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans. Blood 2012 119:1570-1580.

Srinivasan, M and Frauwirth, K.A. (2009). Peripheral Tolerance in CD8 T cells. Cytokine 2009 May; 46(2):147-59.

Srinivasan, M. and K.A. Frauwirth (2007). Reciprocal NFAT1 and NFAT2 nuclear localization in CD8+ anergic T cells is regulated by sub-optimal calcium signaling. J Immunol 2007 179: 3734-3741.

Research and Conference Presentations

Srinivasan, M and KA Frauwirth. "Impaired calcium activity in anergic T cells leads to differential nuclear translocation of NFAT1 and NFAT2 which might result in altered transcription of activation and anergy specific genes." Lymphocyte Activation and Signaling, Keystone conference. Snowbird, Utah. February 2008.

Srinivasan, M and KA Frauwirth. "Reciprocal NFAT1 and NFAT2 nuclear localization in anergic T cells is determined by sub optimal calcium signaling." Immunology 2007, the 94th annual meeting of the American Association of Immunologists, Miami Beach, Florida. May 2007.

Srinivasan, M and KA Frauwirth. "Differential Regulation of Nuclear Localization of NFAT Isoforms in Anergic CD8+ T Cells." Graduate Research Interaction Day (GRID). UMD, College Park. April 2007.

Srinivasan, M and KA Frauwirth. "Defective Calcium Signaling in Anergic T Cells causes Reciprocal Translocation Regulation of NFAT Isoforms." Molecular and Cell Biology Annual Retreat, UMD, College Park. May 2006.

Srinivasan, M and KA Frauwirth. "Defective calcium signaling in anergic T cells causes differential nuclear translocation of NFAT Isoforms." Lymphocyte Activation and Signaling, Keystone conference. Steamboat Springs, Colorado. January 2006.

Previous Positions or Appointments

  • Post-doctoral associate, in the lab of Dr. Bruce Blazar, University of Minnesota, Twin Cities.
  • Research assistant, in the lab of Dr. Kenneth Frauwirth, University of Maryland, College Park.
  • Research assistant, in the lab of Dr. David Mosser, University of Maryland, College Park.
  • Internship, under the guidance of Dr. Saman Habib, Central Drug Research Institute, Lucknow, India.
  • Undergraduate project, under the guidance of Dr. Utpal Roy, Birla Institute of Technology and Science, Pilani.

Post-Doctoral Fellow

Pharmaceutical Research Institute (PRI)

mathangi.srinivasan8@gmail.com
Tel:  (518) 694-7573