Luciana Lopes, Ph.D.

Assistant Professor
Department of Pharmaceutical Sciences, Albany Campus 
Tel: (518) 694-7113
E-mail: luciana.lopes@acphs.edu

Education:

• Ph.D., Pharmacy School of Ribeirao Preto, University of Sao Paulo, Brazil
  
  Pharm.D., Pharmacy School of Ribeirao Preto, University of Sao Paulo, Brazil

Courses Taught at ACPHS:

• Pharmaceutical Analytical Techniques I
  
  Pharmaceutics I and II

Research Interests:

• Dr. Lopes is interested in the topical and transdermal delivery of drugs. The use of the skin as an administration route offers several advantages, but the barrier function of the highly organized structure of the stratum corneum limits its use. The research conducted by Dr. Lopes is focused on the development and evaluation of drug delivery systems as strategies to overcome the barrier function of the stratum corneum, and promote an efficient delivery of therapeutic compounds into or across the skin.

Selected Publications:

• Lopes, L.B., Furnish, E.J., Komalavilas, P, Flynn, C.R., Ashby P., Hansen, A., Ly, D.P., Yang, G.P., Longaker, M.T., Panitch, A., Brophy, C.M. Cell permeant peptide analogues of the small heat shock protein, HSP20, reduces TGF-ß1 induced CTGF expression in keloid fibroblasts. J. Invest. Dermatol. 
  
  Lopes L.B., Furnish E., Komalavilas P., Seal B.L., Panitch A., Bentley M.V., Brophy C.M. Enhanced skin penetration of P20 phosphopeptide using protein transduction domains. Eur. J. Pharm Biopharm., 68:441-5, 2008. 
  
  Lopes, L.B., Lopes, J.L.C., Oliveira, D.C.R., Thomazini, J.A., Garcia, M.T.J., Fantini, M.C.A., Collett, J.H., Bentley, M.V.L.B. Liquid crystalline phases of monoolein and water for topical delivery of cyclosporin A: characterization and study of in vitro and in vivo delivery. Eur. J. Pharm. Biopharm., 63:146-55, 2006. 
  
  Lopes, L.B., Ferreira, D.A., De Paula, D., Garcia, M.T.J., Thomazini, J.A. Fantini, M.C.A., Bentley, M.V.L.B. Reverse hexagonal phase nanodispersion of monoolein and oleic acid for topical delivery of peptides: in vitro and in vivo skin penetration of cyclosporin A. Pharm. Res. 23:1332-42, 2006. 
  
  Lopes, L.B., Brophy, C.M., Furnish E., Flynn, C.R., Sparks, O., Komalavilas, P., Joshi, L., Panitch, A., Bentley, M.V.L.B. Comparative study of the skin penetration of protein transduction domains and a conjugated peptide. Pharm. Res., 22:750-7, 2005.